Moleküler patoloji laboratuvarımızda "Yeni Nesil DNA Dizileme" (New Generation DNA Sequencing) NGS yapılmaktadır.
Mevcut NGS panellerimiz:
Lung Panel
STK11, TP53, SMARCA2, SMARCA2, NTRK1, NTRK2, NTRK3, CHEK1, APC, CREBBP, DNMT3A, NOTCH3, TERT, TET2, POLE, BRCA1, ALK, AKT1, AKT2, AKT3, ATM, ARID1A, ATRX, CDKN2A, CTNNB1, DDR2, MSH6, ERBB2, ERBB4, ESR1, FAT1, FGFR1, FGFR2, FGFR3, FLT3, HRAS, KEAP1, KIT, MAP2K1, MET, NF1, BRAF, EGFR, KRAS, NRAS, TERT, FGFR4, MAP2K2, NOTCH1, NOTCH2, NOTCH4, PDGFRA, PIK3CA, PTEN, PTPRD, PTPRT, RB1, RET, ROS1, RICTOR, SETD2, MTOR, IDH1, ERBB3, BAP1, BRCA2Yeni Eklenenler: PIK3R1, KDM5C, MDM2, NFE2L2, ERCC1, CD274, RASA1, MSI, SMAD4, RAD51
Solid Tümör Paneli
AKT1, CDK12, ALK, APC, ATM, ARID1A, BRCA1, BRCA2, CDKN2A, DDR2, CTNNB1, POLE, ERBB2, ERBB3, ERBB4, CCNE1, MTOR, FGFR1, FGFR2, FGFR3, FLT3, GNAS, GNAQ, GNA11, HRAS, IDH1, IDH2, KIT, MAP2K1, MET, NF1, NOTCH1, MDM-2, MPL, CCND1, PDGFRA, PIK3CA, PTEN, MAP2K2, CDK4, CSF1R, RB1, BRAF, EGFR, KRAS, NRAS, TERT, RET, ROS1, SETD2, SMAD4, TP53, TSC1, TSC2, VHL, AURKA, RAF-1, MYC, NTRK1, ESR1, PIK3R1, PTPN11, SRC, CHEK2, NTRK2, EPCAM, NTRK3, MLH1Yeni Eklenenler: TFE3, TFEB, STK11, JAK1, ARID1B, KEAP1, SMARCA4, SMARCB1, PIK3CB, MSI, NBN, PIK3CG, TCEB1, JAK2
Hematoonkoloji Paneli
FLT3, NPM1, CEBPA, RUNX1, KIT, IDH1, IDH2, TP53, JAK2, MPL, CALR, CSF3R, SETBP1, SRSF2, TET2, U2AF1, ASXL1, EZH2, CBL, GATA2, RUNX1, STAG2, ZRSR2, PTPN11, WT1, EZH2, ARID1A, MEF2B, EP300, CXCR4, STAT6, XPO1, FOXP1, ATM, JAK3, SMARCA4, EZH1, MYC, STAT5B, FOXO1, CREBBP, CARD11, BRAF, KRAS, NRAS, KLF2, PTPRD, BTK, PLCG2, NOTCH1, NOTCH2, CDKN2A, BIRC3, TRAF2, SF3B1, MYD88, CD79A, CD79B, ID3, TCF3, JAK1, STAT3, DNMT3A, RHOA, SETD2Yeni Eklenenler: BCORL1, IL7R, TAL1, ETV6, PRPF8, BCL6, FOXO3, NFKB2, TET3, BCOR, KMT2A, NFKB1, TAL2, BCL2, DNMT3B, SF3A1, MCL1, IKZF1
Genel Füzyon Paneli
TACC3, MET, TFG, PTPRZ1, KIF5B, DRB1, CLIP2, CD74, EPS15, LMNA, MPRIP, NFASC, TFG, TPR, IRF2BP2, TPM3, ETV6, BCR, STRN, TRAF2, AFAP1, AGBL4, GKAP1, BTBD1, EML4, ETV6, HNRNPA2B1, KANK1, ERG, ETV1, ETV4, ETV5, NRG1, CD74, SLC3A2, APP, ATP1B1, RELA, c1lorf95, YAP1, MAMLD1, NTRK1, NTRK2, NTRK3, FGFR2, FGFR3, ALK, TMPRSS2, EML4, NPM1, CLTC, TPM3, RANBP2, STRN, ATIC, KIF5B, TPM4, TFG, HIP1, DCTN1, CARS, PPFIBP1, MSN, VCL, CCDC6, CAD, BRAF, ZKSCAN1, TRIM24, SND1, PPFIBP2, PCBP2, PAPSS1, MKRN1, KIAA1549, GTF21, FAM131B, CUL1, ARMC1O, AKAp9, AGK, AGAP3, SPTLC2, ZMYM4, TACC3, PPHLN1, OPTNYeni Eklenenler: ABL1, FGFR1, TFE3, RET, EWSR1, PDGFRB, NAB2-STAT6, PAX3-FOXO1, BCOR, ROS1
Panellerimizde çıkarılan gen yoktur.
Panel güncellemesi: Ekim 2024
